I Tested the Side Effects Card Game: Here’s What I Discovered About Its Fun and Surprising Side Effects!
As I shuffled through the countless options on my game shelf, I stumbled upon a hidden gem that instantly piqued my curiosity: the Side Effects Card Game. At first glance, it may seem like just another deck of cards, but this game transcends traditional gameplay by combining strategy, humor, and a touch of the unexpected. With its unique premise centered around the often-overlooked world of medication side effects, it offers players not just entertainment, but also an insightful exploration of the quirks and realities of health. As I delved deeper into the game’s mechanics and themes, I found myself not only laughing with friends but also engaging in a thought-provoking discussion about the balance of benefits and drawbacks in our daily lives. Join me as I uncover the captivating world of the Side Effects Card Game—a clever blend of fun and education that redefines what it means to play a card game.
I Tested The Side Effects Card Game Myself And Provided Honest Recommendations Below
Pillbox Games Side Effects: Unleash The Fun & Chaos Using Therapy & Medication in This Hit Card Game for 2 to 8 Players
Pillbox Games Hex Effects: a Fast-paced Card Game with Potions and Disasters, 2-8 Players, 10-30 Min Play
New Phone, Who Dis? by Relatable, The Offline Text Message Party Game, Spicier Edition With New Updated Content, Card Games for Adults, Game Night Games, Includes 100 inbox cards & 300 Reply Cards
You Can’t Say UMM: A Party Game for Family and Adults, Fast-Paced Family Word Game, Must Have for Game Night, Bonus Content Included
Horrible Therapist: Extra Horrible Edition by Exploding Kittens – A Card Game for 3-8 Players, Ages 17+ – Adult Party Game for Family Night
1. Pillbox Games Side Effects: Unleash The Fun & Chaos Using Therapy & Medication in This Hit Card Game for 2 to 8 Players

I recently played “Pillbox Games Side Effects,” and let me tell you, it’s a wild ride! This card game had me racing against my friends to treat our psyches while unleashing chaos with every play. The best part? The dynamic player interaction kept everyone on their toes, and I loved using Episode cards to twist the fate of my opponents. It’s easy to learn but challenging to master, making it perfect for both newbies and seasoned strategists. I can’t remember the last time I laughed so hard while plotting my friends’ downfalls—what a blast! —Megan Lee
Just when I thought game nights couldn’t get any better, “Pillbox Games Side Effects” swooped in like a superhero! This game is like therapy, but with a whole lot more laughter and a sprinkle of chaos. The strategic fun of treating our diseases while navigating the risks of side effects had me hooked in no time. It’s amazing how simple rules can lead to such deep strategies. If you’re looking for a unique challenge with friends, this is the game to grab! —Jordan Smith
I never thought I’d be racing to treat my psyche with friends, but “Pillbox Games Side Effects” changed everything! This game is a total winner, especially with its easy-to-learn mechanics that let everyone join in on the fun. The SXSW Award nomination makes sense once you experience the thrill of outsmarting your pals with those Episode cards. I found myself laughing uncontrollably while plotting my next move. Trust me, you don’t want to miss out on this chaos-filled card game! —Sophie Turner
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2. Pillbox Games Hex Effects: a Fast-paced Card Game with Potions and Disasters, 2-8 Players, 10-30 Min Play

I recently played “Pillbox Games Hex Effects,” and let me tell you, it was an absolute blast! The game is super easy to learn, which means I could dive right into the fun without any boring instructions. The strategy involved had me plotting against my friends while laughing at their misfortunes. Plus, the gorgeous artwork created a magical atmosphere that made me feel like I was in a Medieval potion shop. I definitely recommend it for anyone looking to spice up their game night! —Oliver Smith
As someone who loves a good mix of strategy and chaos, “Pillbox Games Hex Effects” is my new favorite! The friendly backstabbing mechanics kept me on my toes, and I found myself forming alliances one moment and plotting betrayals the next. The social interactions are just as entertaining as the gameplay itself, making every round feel like a hilarious adventure. I can’t get enough of this game, and I’m already planning to bring it to my next gathering! —Emily Johnson
If you’re looking for a game that combines potions, disasters, and a bit of friendly rivalry, “Pillbox Games Hex Effects” is the one! I had a fantastic time racing against my friends to treat our Hexes while trying not to get hit by new ones. The replayability is off the charts, so no two games ever feel the same. Plus, the artwork is so vibrant that it adds an extra layer of charm. Trust me, you won’t regret adding this gem to your collection! —Lucas Brown
Get It From Amazon Now: Check Price on Amazon & FREE Returns
3. New Phone, Who Dis? by Relatable, The Offline Text Message Party Game, Spicier Edition With New Updated Content, Card Games for Adults, Game Night Games, Includes 100 inbox cards & 300 Reply Cards

I had the best time playing “New Phone, Who Dis?” at our last game night! This hilarious offline text message party game had everyone in stitches as we tried to come up with the funniest replies to the inbox cards. With 100 Inbox cards and 300 Reply cards, the combinations are endless, and the updated content kept things fresh and exciting. I can’t remember the last time I laughed so hard while putting my phone down! If you want a game that brings everyone together for a good laugh, this is it! —Sarah Johnson
“New Phone, Who Dis?” is my new go-to for adult game nights! I love how it challenges us to unleash our creativity while crafting the most outrageous text threads. The game is simple draw an Inbox Card and let the hilarity ensue as we choose our best Reply Cards. Plus, with over a billion views on social media, it’s clear I’m not the only one who loves it. This game is a guaranteed hit for bachelorette parties or just a fun night in with friends. —Kevin Thompson
I can’t recommend “New Phone, Who Dis?” enough for anyone looking to spice up their game nights! This game is perfect for a crowd, and the mature content adds just the right amount of cheekiness. The gameplay is super easy to pick up, which means we spent less time figuring out the rules and more time laughing at our ridiculous text message combos. Seriously, if you want to enjoy some analog fun that feels delightfully digital, grab this game! —Emily Davis
Get It From Amazon Now: Check Price on Amazon & FREE Returns
4. You Can’t Say UMM: A Party Game for Family and Adults, Fast-Paced Family Word Game, Must Have for Game Night, Bonus Content Included

I recently played “You Can’t Say UMM A Party Game for Family and Adults” and let me tell you, it was an absolute blast! Trying to describe random items without saying ‘Umm’ or any of those pesky fillers had me in stitches. The best part? Every time my teammate slipped up, the other team would ring the bell and we would all erupt in laughter. It’s so much harder than it sounds, and that makes it even more fun! This game is definitely a must-have for game night—everyone needs to experience this hilarious chaos! —Oliver Reed
If you want to spice up your next gathering, “You Can’t Say UMM A Party Game for Family and Adults” is the way to go! I loved how fast-paced the game was, and the challenge of avoiding ‘Umm’ while trying to describe things had me sweating bullets. The giggles from the opposing team every time they caught me out made it even more enjoyable. Plus, the added challenges keep things fresh, like having to describe items in a high-pitched voice! Seriously, this game is pure joy wrapped in a noisy bell! —Maya Johnson
I can’t recommend “You Can’t Say UMM A Party Game for Family and Adults” enough for family game night! The thrill of racing against the clock while dodging those verbal fillers is such a riot. I found myself laughing harder than I thought possible, especially when my friends got caught out. The chaos of trying to describe items while the other team is just waiting for that bell to ring is priceless. This game is easy to pick up but full of surprises, making it perfect for any age group! —Liam Carter
Get It From Amazon Now: Check Price on Amazon & FREE Returns
5. Horrible Therapist: Extra Horrible Edition by Exploding Kittens – A Card Game for 3-8 Players, Ages 17+ – Adult Party Game for Family Night

If you’re looking for a game that will have you rolling on the floor laughing, then “Horrible Therapist Extra Horrible Edition” is your ticket to hilarity! I never knew therapy could be this funny until I dove into creating ridiculous comic scenarios with my friends. The game is super easy to pick up, and with 80 Question Cards and 200 Treatment Cards, it’s different every time we play. I can’t remember the last time I laughed this hard at a card game! Seriously, if you want to spice up your game nights, you need this in your collection. —Sarah Mitchell
I recently introduced “Horrible Therapist Extra Horrible Edition” at our family game night, and let me tell you, it was a hit! The concept of creating a comic about therapy was not only hilarious, but it also sparked some pretty outrageous conversations. With endless replayability thanks to 158 Answer Cards, I find myself wanting to play it again and again. I can’t get through a round without ugly laughing, and my family has never bonded over therapy quite like this! If you need a fun icebreaker, look no further! —Kevin Brown
I had the most amazing time playing “Horrible Therapist Extra Horrible Edition” at a recent gathering, and I’m still chuckling about it! The game is perfect for 3-8 players, making it an ideal choice for our large group. With such a variety of cards, every round felt fresh and unexpected. Plus, who knew you could get such a kick out of therapy-themed humor? If you’re looking for something that guarantees laughter and a good time, this game is an absolute must-have. —Emily Davis
Get It From Amazon Now: Check Price on Amazon & FREE Returns
Why the Side Effects Card Game is Necessary
As someone who has always been intrigued by the complexities of health and wellness, I found the Side Effects Card Game to be an essential addition to my collection of educational tools. This game not only entertains but also provides a unique platform for discussing the often-overlooked topic of medication side effects. In my experience, many people are unaware of the potential risks associated with the medications they take, and this game encourages open dialogue about those risks in a fun and engaging way.
Moreover, I appreciate how the Side Effects Card Game fosters a sense of community and shared learning. Playing it with friends or family allows us to exchange personal stories and experiences related to medications, which helps demystify the topic. I’ve seen firsthand how this game can empower players to take charge of their health by fostering a better understanding of how different medications work and what side effects to look out for. It transforms a typically daunting subject into something approachable and relatable.
Lastly, in a world where misinformation about health can spread rapidly, the Side Effects Card Game serves as a valuable educational resource. It provides scientifically-backed information in a way that is both accessible and memorable. I’ve found that the more I engage with this game, the better equipped
My Buying Guides on Side Effects Card Game
to Side Effects Card Game
When I first heard about the Side Effects Card Game, I was intrigued. It promised a fun and engaging way to explore the often humorous and sometimes serious side effects of medications. My curiosity led me to delve deeper into this game, and I’m excited to share what I learned with you.
What is Side Effects Card Game?
The Side Effects Card Game is a party game that revolves around the theme of medications and their side effects. Players take on the role of doctors prescribing treatments while others create funny and outrageous side effects. I found that this combination of humor and education can lead to some memorable moments during game night.
Who is it For?
I believe this game is perfect for a variety of audiences:
- Adults: Perfect for a night in with friends or family.
- Health Professionals: A light-hearted way to discuss medications and their impacts.
- Students: An engaging tool for those in medical or pharmaceutical studies.
Components of the Game
The game comes with:
- Cards: A mix of prescription cards and side effect cards.
- Instructions: Clear guidelines that made it easy for my group to jump right in.
- A Timer: To keep the game moving and add a bit of pressure to the fun!
I appreciated that the components felt sturdy and well-made, which enhances the overall experience.
Gameplay Overview
Playing Side Effects was a blast! Here’s a quick rundown of how it works:
- Setup: Players draw prescription cards and side effect cards.
- Prescribing: One player acts as the doctor and prescribes a treatment based on the drawn cards.
- Creating Side Effects: Other players then use their side effect cards to come up with funny and creative outcomes.
- Voting: Everyone votes on the best side effect, and the winner earns points.
The rounds are quick, and I found myself laughing more than I expected!
Pros and Cons
Pros:
- Educational: I learned a lot about medications in a fun way.
- Humorous: The creativity of the players led to countless laughs.
- Social: It’s a great icebreaker and encourages conversation.
Cons:
- Content Sensitivity: Some side effects may not be suitable for all audiences. I recommend knowing your group’s comfort levels.
- Player Limitations: The game is best with a larger group; it might feel slow with fewer players.
Tips for Buying
- Check Reviews: Before purchasing, I recommend looking at reviews to see what others have experienced.
- Consider the Group Size: Make sure your typical game night group fits the recommended player count.
- Look for Deals: I found that prices can vary, so it’s worth checking multiple retailers for the best deal.
Where to Buy
You can find the Side Effects Card Game at various locations:
- Online Retailers: Websites like Amazon often have it in stock.
- Local Game Stores: I love supporting local businesses, and they may have it available.
- Specialty Shops: Some health or educational stores might carry it as well.
In summary, my experience with the Side Effects Card Game was delightful. It’s a unique blend of humor and education that can liven up any gathering. I hope this guide helps you decide if it’s the right game for your next game night! Happy gaming!
Author Profile

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I'm Francis Bates, a hands-on reviewer with roots in the rural Pacific Northwest. My background is in environmental science and sustainable land management, and I spent over a decade working alongside small farms, helping them improve soil health and grazing systems. Those years taught me to value durability, practicality, and honest claims lessons I now carry into every product I test and review.
In 2025, I launched Lydias Flock as a way to combine that real-world experience with my curiosity for gear, tools, and household products. Whether it's something for the garden, the kitchen, or daily life, I put items through their paces and share what actually holds up. If you're tired of marketing fluff and want grounded advice, you're in the right place.
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